P59. Logé, C.; Testard, A.; Thiery, V.; Lozach, O.; Blairvacq, M.; Robert, J-M.; Meijer, L.; Besson, T. Novel 9-oxo-thiazolo[5,4-f]quinazoline-2-carbonitrile derivatives as dual cyclin-dependent kinase 1 (CDK1) / glycogen synthase kinase-3 (GSK-3) inhibitors: synthesis, biological evaluation and molecular modeling studies. Eur. J. Med. Chem., 2008, 43(7), 1469-1477.


P60. Dassonville, A.; Lardic, M.; Breteche, A.; Nourrisson, M-R.; Le Baut, G.; Grimaud, N.; Petit, J-Y.; Duflos, M. N-Pyridinyl(methyl)-indole-1- or 3-propanamides and propenamides acting as topical and systemic anti-inflammatory inhibitors. J. Enz. Inh. Med. Chem. 2008, 23(5), 728-738.

 

P61. Kaessler, A.; Nourrisson, M-R.; Duflos, M.; Jose, J. Indole carboxamides inhibit bovine testes hyaluronidase at pH 7.0 and indole acetamides activate the enzyme at pH 3.5 by different mechanisms. J. Enz. Inh. Med. Chem. 2008, 23(5), 719-727.

 

P62. Le Pape, P. Development of new antileishmanial drugs - current knowledge and future prospects. J. Enz. Inh. Med. Chem. 2008, 23(5), 708-718.

 

P63. Antoine, M.; Marchand, P.; Le Baut, G.; Czech, M.; Baasner, S.; Gunther, E. Side chain modifications of (indol-3-yl)glyoxamides as antitumor agents. J. Enz. Inh. Med. Chem.2008, 23(5), 686-695.

 

P64. Sabourin, C.; Robert, J-M. Synthesis and immunosuppressive activity evaluation of substituted N-imidazolidin-2-ones and N-tetrahydropyrimidin-2(1H)-ones. J. Enz. Inh. Med. Chem. 2008, 23(5), 659-667.

 

P65. Farard, J.; Lanceart, G.; Logé, C.; Nourrisson M-R.; Cruzalegui, F.; Pfeiffer, B.; Duflos, M. Design, synthesis and evaluation of new 6-substituted-5-benzyloxy-4-oxo-4H-pyran-2-carboxamides as potential Src inhibitors. J. Enz. Inh. Med. Chem. 2008, 23(5), 629-640. + erratum

 

P66. Hay, A.E.; Merza, J.; Landreau, A.; Litaudon, M.; Pagniez, F.; Le Pape, P.; Richomme, P. Antileishmanial polyphenols from Garcinia vieillardii. Fitoterapia, 2008, 79(1), 42-46.

 

P67. Kerzaon, I.; Grovel, O.; Robiou Du Pont, T.; Le Pape, P.; Pouchus, Y-F. Effects of seawater on growth and gliotoxin excretion of marine strains of Aspergillus fumigatus Fres. Toxicon 2008, 51(3), 398-405.

 

P68. Jacquemard, U.; Dias, N.; Lansiaux, A.; Bailly, C.; Logé, C.; Robert, J-M.; Lozach, O.; Meijer, L.; Mérour, J-Y.; Routier, S. Synthesis of 3,5-bis(2-indolyl)pyridine and 3-[(2-indolyl)-5-phenyl]pyridine derivatives as CDK inhibitors and cytotoxic agents. Bioorg. Med. Chem. 2008, 16(9), 4932-4953.

 

P69. Lézé, M-P.; Palusczak, A.; Hartmann, R.W.; Le Borgne, M. Synthesis of 6- or 4-functionalized indoles via a reductive cyclization approach and evaluation as aromatase inhibitors. Bioorg. Med. Chem. Lett. 2008, 18(16), 4713-4715.

 

P70. Giraud, F.; Logé, C.; Pagniez, F.; Crepin, D.; Le Pape, P.; Le Borgne, M. Design, synthesis, and evaluation of 1-(N-benzylamino)-2-phenyl-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as antifungal agents. Bioorg. Med. Chem. Lett. 2008, 18(6), 1820-1824.

 

P71. Hennequin, C.; Ancelle, T.; Beretta, S. 41 French Biologists. Outbreaks of nosocomial candidiasis in France 1996-2006. J. Hosp. Infect. 2008, 68(4), 377-380.

 

P72. Guillouzouic, A.; Bemer, P.; Gay-Andrieu, F.; Bretonnière, C.; Lepelletier, D.; Mahé, P-J.; Villers, D.; Jarraud, S.; Reynaud, A.; Corvec, S. Fatal coinfection with Legionella pneumophila serogroup 8 and Aspergillus fumigatus. Diagn. Microbiol. Infect. Dis. 2008, 60(2), 193-195.

 

P73. Morio, F.; Treilhaud, M.; Lepelletier, D.; Le Pape, P.; Rigal, J-C.; Delile, L.; Robert, J-P.; Al Habash, O.; Miegeville, M.; Gay-Andrieu, F. Aspergillus fumigatus endocarditis of the mitral valve in a heart transplant recipient: a case report. Diagn. Microbiol. Infect. Dis. 2008, 62(4), 453-456.