P142. Antoine, M.; Schuster, T.; Seipelt, I.; Aicher, B.; Teifel, M.; Günther, E.; Gerlach, M.; Marchand, P. Efficient synthesis of novel disubstituted pyrido[3,4-b]pyrazines for the design of protein kinase inhibitors. Med. Chem. Commun. 2016, 7, 224-229.

P143. Le Pape, P.; Lavergne, R.-A.; Morio, F.; Alvarez-Moreno, C. Multiple fungicide-driven alterations in azole-resistant Aspergillus fumigatus, Colombia, 2015. Emerg. Infect. Dis. 2016, 22, 156-157.

P144. Sakanyan, V.; Hulin, P.; Alves de Sousa, R.; Silva, V. A.; Hambardzumyan, A .; Nedellec, S.; Tomasoni, C.; Logé, C.; Pineau, C.; Roussakis, C.; Fleury F.; Artaud, I. Activation of EGFR by small compounds through coupling the generation of hydrogen peroxide to stable dimerization of Cu/Zn SOD1. Sci. Rep. 2016, 6, 21088, doi:10.1038/srep21088.

P145. Tadec, L.; Talarmin, J.P.; Gastinne, T.; Bretonnière, C.; Miegeville, M.; Le Pape, P.; Morio, F. Epidemiology, risk factor, species distribution, antifungal resistance and outcome of Candidemia at a single French hospital: a 7-year study. Mycoses 2016, 59, 296-303.

P146. Hossain, M.A.; Lalloz, A.; Benhaddou, A.; Pagniez, F.; Raymond, M.; Le Pape, P; Simard, P.; Théberge, K.; Leblond, J. Econazole imprinted textiles with antifungal activity. Eur. J. Pharm. Biopharm. 2016, 101, 137-144.

P147. Alvarez-Rueda, N.; Fleury, A.; Logé, C.; Pagniez, F.; Robert, E.; Morio, F.; Le Pape, P. The amino acid substitution N136Y in Candida albicans sterol 14alpha-demethylase is involved in fluconazole resistance. Med. Mycol. 2016, 54, 764-75.

P148. Bazin, M.-A.; Rousseau, B.; Marhadour, S.; Tomasoni, C.; Evenou, P.; Piessard, S.; Vaisberg, A. J.; Ruchaud, S.; Bach, S.; Roussakis, C.; Marchand, P. Discovery of (imidazo[1,2-a]pyrazin-6-yl)ureas as antiproliferative agents targeting P53 in non-small cell lung cancer cell lines. Anticancer Res. 2016, 36, 1621-1630.

P149. Montoir, D.; Barillé-Nion, S.; Tonnerre, A.; Juin, P.; Duflos, M.; Bazin, M.-A. Novel 1,6-naphthyridin-2(1H)-ones as potential anticancer agents targeting Hsp90. Eur. J. Med. Chem. 2016, 119, 17-33.

P150. Bougnoux, M.-E.; Dannaoui, E.; Accoceberry, I.; Angoulvant, A.; Bailly, E.; Botterel, F.; Chevrier, S.; Chouaki, T.; Cornet, M.; Dalle, F.; Datry, A.; Dupuis, A.; Fekkar, A.; Gangneux, J.-P.; Guitard, J.; Hennequin, C.; Le Govic, Y.; Le Pape, P.; Maubon, D.; Ranque, S.; Sautour, M.; Sendid, B.; Chandenier, J. Multicenter Comparison of the Etest and EUCAST Methods for Antifungal Susceptibility Testing of Candida Isolates to Micafungin. Antimicrob. Agents Chemother. 2016, 60, 5088-5091.

P151. Rodríguez, J. Y.; Rodríguez, G. J.; Morales-López, S. E.; Cantillo, C. E.; Le Pape, P.; Álvarez-Moreno C. A. Saksenaea erythrospora infection after medical tourism for esthetic breast augmentation surgery. Int. J. Infect. Dis. 2016, 49, 107-110.

P152. Silva, V. A.; Lafont, F.; Benhelli-Mokrani, H.; Breton, M. L.; Hulin, P.; Chabot, T.; Paris, F.; Sakanyan, V.; Fleury, F. Rapid Diminution in the Level and Activity of DNA-Dependent Protein Kinase in Cancer Cells by a Reactive Nitro-Benzoxadiazole Compound. Int. J. Mol. Sci. 2016, 17, E703, doi: 10.3390/ijms17050703.

P153. Sakanyan, V.; Benaiteau, F.; Alves de Sousa, R.; Pineau, C.; Artaud, I. Straightforward Detection of Reactive Compound Binding to Multiple Proteins in Cancer Cells: Towards a Better Understanding of Electrophilic Stress. Ann. Clin. Exp. Metabol. 2016, 1, 1006.

P154. Haas, M.; Grenouillet, F.; Loubersac, S.; Ariza, B.; Pepin-Puget, L.; Alvarez, C.; Valderrama, S.; Lavergne, R.-A.; Le Pape, P.; Morio, F. Identification of cryptic Candida species by MALDI-TOF mass spectrometry, not all MALDI-TOF systems are the same: focus on the C. parapsilosis species complex. Diagn. Microbiol. Infect. Dis. 2016, 86, 385-386.