The team
Department of Medicinal Chemistry
The department of Medicinal Chemistry is involved in Drug Discovery, i.e. the design, synthesis, purification, structural elucidation and study of structure-activity relationships of original heterocyclic molecules as antifungal, antiparasitic and antibacterial drug candidates. The physicochemical and ADME-Tox properties of compounds of biological interest are also discussed in all the projects.
Teacher-researchers
Professor - Head of Department
Associate Professor
Professor
Associate Professor
Professor
Visiting Scientist
Attaché Temporaire d'Enseignement et de Recherche
Technical staff
Post-doctoral researcher
Other departments
The Department of Bacterial Resistances studies how interactions between the host, its microbiota and drugs (particularly anti-infective drugs, but not exclusively) influence bacterial resistance to antibiotics. We are working in particular on digestive colonisation by multi-resistant Enterobacteriaceae, and are testing the possibility of treating this colonisation with live bacteria ('probiotics') or polysaccharides ('prebiotics'). We are also working on improving the use of antibiotics, with the aim of ensuring effective treatment of bacterial infections (particularly pneumonia and community-acquired urinary tract infections) while minimising the risk of emergence, persistence and spread of multi-resistant bacteria.
The Department of Medical Mycology and Parasitology is supported by university and hospital-university staff, enabling it to focus on health-related issues. Research strategies benefit from expertise in cell culture, signalling, molecular biology, immunology applied to microbiology, recombinant protein production (P2R platform) and in vivo models. Its activities focus mainly on resistance issues and the discovery of new therapeutic targets.