Robert, J.-M. | IICIMED

Robert, J.-M.

Professeur

Publications

P285

Int. J. Pharm. Res. Al. Sci. 2024, 13, 1-11.

Design and synthesis of functionalized 2,4-diamino-1,3,5-triazines, potential inhibitors involved in immune and inflammatory response.

Sika Diakite, A. | Ambeu, C. | Yapi, A.D. | Logé, C. | Kacou, A. | Kra, S. | Baratte, B. | Bach, S. | Ruchaud, S. | Sissouma, D. | Ouattara, M. | Robert, J.-M.

https://doi.org/10.51847/hsT2C61XWx

P206

Role of JAK inhibitors and immune cells in transplantation.

Sailliet, N. | Brosseau, C. | Robert, J.-M. | Brouard, S.

doi: 10.1016/j.cytogfr.2019.05.002

P196

ChemBioChem 2019, 20, 2255-2261.

Rapid synthesis and antiproliferative properties of polyazamacrocycle-based bi- and tetra-gold(I) phosphine dithiocarbamate complexes.

Flores, O. | Velic, D. | Mabrouk, N. | Bettaieb, A. | Tomasoni, C. | Robert, J.-M. | Paul, C. | Goze, C. | Roussakis, C. | Bodio, E.

doi: 10.1002/cbic.201900227

P184

Haspin: a promising target for the design of inhibitors as potent anticancer drugs.

Amoussou, N. G. | Bigot, A. | Roussakis, C. | Robert, J.-M.

doi : 10.1016/j.drudis.2017.10.005

P182

Tetrahedron Lett. 2018, 59, 3519-3523.

Novel approach towards 3,7-disubstituted 1,6-naphthyridin-4(1H)-ones exploiting cross-coupling and SNAr reactions of a dihalogenated compound.

Dembélé, O. | Montoir, D. | Yvorra, T. | Sérillon, D. | Tonnerre, A. | Duflos, M. | Robert, J.-M. | Bazin, M.-A.

doi: 10.1016/j.tetlet.2018.08.013

P131

Bioorg. Med. Chem. Lett. 2014, 24, 5037-5040.

Synthesis of new pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs as DYRK1A inhibitors.

Bruel, A. | Bénéteau, R. | Chabanne, M. | Lozach, O. | Le Guével, R. | Ravache, M. | Bénédetti, H. | Meijer, L. | Logé, C. | Robert, J.-M.

P106

J. Med. Chem., 2012, 57, 225-233.

Synthesis and biological evaluation of new 5-benzylated 4-oxo-3,4-dihydro-5H-pyridazino[4,5-b]indoles as PI3K inhibitors. Eur.

Bruel, A. | Logé, C. | de Tauzia, M.-L. | Ravache, M. | Le Guevel, R. | Guillouzo, C. | Lohier, J.-F. | Sopkova-de Oliveira Santos, J. | Lozach, O. | Meijer, L. | Ruchaud, S. | Bénédetti, H. | Robert, J.-M.

Autres publications scientifiques

PS20

Front. Immunol. 2023, 14, 1183714. 

Human granzyme B regulatory B cells prevent effector CD4+CD25- T cell proliferation through a mechanism dependent from lymphotoxin alpha.

Sailliet, N. | Mai H. L. | Dupuy, A. | Tilly, G. | Fourgeux, C. | Braud, M. | Giral, M. | Robert, J.-M. | Degauque, N. | Danger, R. | Poschmann, J. | Brouard, S.

https://doi.org/10.3389/fimmu.2023.1183714

PS03

Int. J. Mol. Sci. 2022, 23, 2923.

Chemical synthesis, pharmacokinetic properties and biological effects of JM-00266, a putative non-brain penetrant cannabinoid receptor 1 inverse agonist. 

Muller, T. | Demizieux, L. | Troy-Fioramonti, S. | Buch, C. | Leemput, J. | Belloir, C. | Pais de Barros, J.-P. | Jourdan, T. | Passilly-Degrace, P. | Fioramonti, X. | Le Bon, A.-M. | Vergès, B. | Robert, J.-M. | Degrace, P.

https://doi.org/10.3390/ijms23062923

Brevets

B16.

1,4-Di-(4-méthylthiophényl)-3-phtaloylazétidine-2-one et dérivés, utilisables dans les maladies métaboliques et le cancer

Robert, J.-M. | Troy-Fiorament, S. | Demizieux, L. | Degrace, P.

Brevet français déposé le 25/09/2015 sous le N° 1559067 ; demande de PCT déposée le 23/09/2016.

Thèse