P142

Eur. J. Med. Chem. 2015, 105, 80-105.

Development of new highly potent imidazo[1,2-b]pyridazines targeting Toxoplasma gondii Calcium-Dependent Protein Kinase 1.

Moine, E. | Dimier-Poisson, I. | Enguehard-Gueiffier, C. | Logé, C. | Penichon, M. | Moire, N. | Delehouze, C. | Foll-Josselin, B. | Ruchaud, S. | Bach, S. | Gueiffier, A. | Debierre-Grockiego, F. | Denevault-Sabourin, C.

doi: 10.1016/j.ejmech.2015.10.004

P141

Tetrahedron 2015, 71, 3303-3313.

Efficient one-pot synthesis of 3,7-disubstituted 1,6-naphthyridin-2(1H)-ones through regioselective palladium-catalyzed cross-coupling and SNAr reactions.

Montoir, D. | Tonnerre, A. | Duflos, M. | Bazin, M.-A.

doi: 10.1016/j.tet.2015.03.110

P140

 Mar. Drugs 2015, 13, 4934-48. 

The Marine-Derived Fungus Clonostachys rosea, Source of a Rare Conjugated 4-Me-6E,8E-hexadecadienoic Acid Reducing Viability of MCF-7 Breast Cancer Cells and Gene Expression of Lipogenic Enzymes.

Dias, A. C. | Ruiz, N. | Couzinet-Mossion, A. | Bertrand, S. | Duflos, M. | Pouchus, Y. F. | Barnathan, G. | Nazih, H. | Wielgosz-Collin, G.

doi: 10.3390/md13084934

P139

Eur. J. Med. Chem. 2015, 92, 124-134.

Synthesis and molecular modelling studies of 8-arylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-amines as multitarget Ser/Thr kinases inhibitors.

Loidreau, Y. | Deau, E. | Marchand, P. | Nourrisson, M.-R. | Logé, C. | Coadou, G. | Loaëc, N. | Meijer, L. | Besson, T.

doi: 10.1016/j.ejmech.2014.12.038

P138

Sci. Rep. 2015, 5:10356

 TP53 transcription factor to NEDD9/HEF1/Cas-L gene: potential targets in Non Small Cell Lung Cancer treatment.

Rousseau, B. | Jacquot, C. | Le Palabe, J. | Malleter, M. | Tomasoni, C. | Boutard, T. | Sakanyan, V. | Roussakis, C.

doi: 10.1038/srep10356

P137

Transpl. Infect. Dis. 2015, 17, 297-302.

Multifocal phaeohyphomycosis caused by Exophiala xenobiotica in a kidney transplant recipient.

Palmisano, A. | Morio, F. | Le Pape, P. | Degli Antoni, A. M., Ricci, R. | Zucchi, A. | Vaglio, A. | Pitti, G. | Antoniotti, R. | Cremaschi, E. | Buzio, C. | Maggiore, U.

doi: 10.1111/tid.12350

P136

Eur. J. Med. Chem. 2015, 103, 381-395.

Synthesis, antileishmanial activity and cytotoxicity of 2,3-diaryl- and 2,3,8-trisubstituted imidazo[1,2-a]pyrazines.

Marchand, P. | Bazin, M.-A. | Pagniez, F. | Rivière, G. | Bodero, L. | Marhadour, S. | Nourrisson, M.-R. | Picot, C. | Ruchaud, S. | Bach, S. | Baratte, B. | Sauvain, M. | Castillo Pareja, D. | Vaisberg, A. J. | Le Pape, P.

doi: 10.1016/j.ejmech.2015.09.002

P135

Antimicrob. Agents Chemother. 2015, 59, 4331-4335.

First description of azole-resistant Aspergillus fumigatus due to TR46/Y121F/T289A mutation in France.

Lavergne, R.-A. | Morio, F. | Favennec, L. | Dominique, S. | Meis, J.-F. | Gargala, G. | Verweij, P.-E. | Le Pape, P.

doi: 10.1128/AAC.00127-15