P206

Role of JAK inhibitors and immune cells in transplantation.

Sailliet, N. | Brosseau, C. | Robert, J.-M. | Brouard, S.

doi: 10.1016/j.cytogfr.2019.05.002

P205

Pharmaceuticals 2019, 12, 182;

A decade of antifungal leads from natural products: 2010-2019.

Aldholmi, M. | Marchand, P. | Ourliac-Garnier, I. | Le Pape, P. | Ganesan, A.

doi:10.3390/ph12040182.

P204

Med. Chem. Commun. 2019, 10, 1916-1925.

Evaluation of anti-inflammatory activity and molecular docking study of new aza-bicyclic isoxazoline acylhydrazone derivatives.

Barreto Mota, F. V. | Saraiva de Araújo Neta, M. | de Souza Franco, E. | Gomes Alves Bastos, I. V. | Cardoso Correia da Araújo, L. | Cabral da Silva, S. | Bezerra de Oliveira, T. | Souza, E. K. | Moraes de Almeida, V. | Matos Ximenes, R. | de Sousa Maia, M. B. | Mendonça Junior, F. J. B. | Marchand, P. | de Faria, A. R. | da Silva, T. G.

doi: 10.1039/c9md00276f

P203

Int. Immunopharmacol. 2019, 76, 105856.

Synthesis and pharmacological evaluation of CVIB, a codrug of carvacrol and ibuprofen as a novel anti-inflammatory agent.

de Oliveira Pedrosa Rolim, M. | Rodrigues de Almeida, A. | Galdino da Rocha Pitta, M. | Barreto de Melo Rêgo, M. J. | Quintans-Júnior, L. J. | de Souza Siqueira Quintans, J. | Heimfarth, L. | Scotti, L. | Scotti, M. T. | Marques Duarte da Cruz, R. | Nóbrega de Almeida, R. | da Silva, T. G. | de Oliveira, J. A. | de Campos, M. L. | Marchand, P. | Mendonça Junior, F. J. B.

doi:10.1016/j.intimp.2019.105856

P202

Pharmaceuticals 2019, 12, 169.

Biological evaluation of arylsemicarbazone derivatives as potential anticancer agents.

Nascimento da Cruz, A. C. | Brondani, D .J. | I´talo de Santana, T. | Oliveira da Silva, L. | da Oliveira Borba, E. F. | de Faria, A. R. | Ferreira Cavalcanti de Albuquerque, J. | Piessard, S. | Matos Ximenes, R. | Baratte, B. | Bach, S. | Ruchaud, S. | Bezerra Mendonça Junior, F. J. | Bazin, M.-A. | Montenegro Rabello, M. | Hernandes, M. Z. | Marchand, P. | Gonçalves da Silva, T.

doi:10.3390/ph12040169

P201

Lipids Health Dis. 2019, 18, 168.

4-cholesten-3-one decreases breast cancer cell viability and alters membrane raft-localized EGFR expression by reducing lipogenesis and enhancing LXR-dependent cholesterol transporters.

Elia, J. | Carbonnelle, D. | Logé, C. | Ory, L. | Huvelin, J.-M. | Tannoury, M. | Diab-Assaf, M. | Petit, K. | Nazih, H.

doi: 10.1186/s12944-019-1103-7

P200

Bioorg. Med. Chem. 2019, 27, 3797-3804.

Thiazolidinedione and thiazole derivatives potentiate norfloxacin activity against NorA efflux pump over expression in Staphylococcus aureus 1199B strains.

Pereira, P. S. | de Lima, M. D. C. A. | Neto, P. P. M. | de Morais Oliveira-Tintino, C. D. | Tintino, S. R. | de Alencar Menezes, I. R. | Ferreira de Oliveira, J. | Marchand, P. | Melo Coutinho, H. D. | do Desterro Rodrigues, M. | da Silva, T. G.

doi: 10.1016/j.bmc.2019.07.006

P199

Curr. Top. Med. Chem. 2019, 19, 1075-1091.

5-Nitro-thiophene-thiosemicarbazone derivatives present antitumor activity mediated by apoptosis and DNA intercalation.

Roque Marques, K. M. | do Desterro, M. R. | de Arruda, S. M. | de-Araújo Neto, L. N. | de Lima, M. D. C. A. | de Almeida, S. M. V. | Silva, E. C. D. D. | Aquino, T. M. | Júnior, E. F. D. S. | Júnior, J. X. D. | Silva, M. M. | de A. Dantas, M. D. | C. Santos, J. C. | Figueiredo, I.M. | Bazin, M.-A. | Marchand, P. | da Silva, T. G. | Mendonça Junior, F. J. B.

doi: 10.2174/1568026619666190621120304

P198

Cancers, 2019, 11, 1094.

Degradation of EGFR through the Allosteric Site Leads to Cancer Cell Detachment-Promoted Death.

Iradyan, M. | Iradyan, N. | Hulin, P. | Hambardzumyan, A. | Gyulkhandanyan, A. | Alves de Sousa, R. | Hessani, A. | Roussakis, C. | Bollot, G. | Bauvais, C. | Sakanyan, V. Targeting

doi: 10.3390/cancers11081094

P197

Mar. Drugs 2019, 17, 372.

Steroids from Marine-Derived Fungi: Evaluation of Antiproliferative and Antimicrobial Activities of Eburicol.

Dos Santos Dias, A. C. | Couzinet-Mossion, A. | Ruiz, N. | Lakhdar, F. | Etahiri, S. | Bertrand, S. | Ory, L. | Roussakis, C. | Pouchus, Y.-F. | Nazih, H. | Wielgosz-Collin, G.

doi:10.3390/md17060372

P196

ChemBioChem 2019, 20, 2255-2261.

Rapid synthesis and antiproliferative properties of polyazamacrocycle-based bi- and tetra-gold(I) phosphine dithiocarbamate complexes.

Flores, O. | Velic, D. | Mabrouk, N. | Bettaieb, A. | Tomasoni, C. | Robert, J.-M. | Paul, C. | Goze, C. | Roussakis, C. | Bodio, E.

doi: 10.1002/cbic.201900227

P195

La lettre de l’infectiologue. Editorial 2019 Tome XXXVI, 6, 234-235

Candida auris: should we fear the emergence of a highly resistant fungi?

Le Pape, P. | Alvarez Moreno, C.

P194

Hum. Immunol. 2019, 80, 999-1005.

Double positive CD4+CD8+ T cells are part of the adaptive immune response against Candida albicans.

Misme-Aucouturier, B. | Touahri, A. | Albassier, M. | Jotereau, F. | Le Pape, P. | Alvarez-Rueda, N.

doi: 10.1016/j.humimm.2019.09.008

P193

BMC Microbiol. 2019, 19, 106.

Comparison between MALDI-TOF MS and MicroScan in the identification of emerging and multidrug resistant yeasts in a fourth-level hospital in Bogotá, Colombia.

Ceballos-Garzón, A. | Cortes, G. | Morio, F. | Zamora-Cruz, EL. | Linares, MY. | Ariza, BE. | Valderrama, SL. | Garzón, JR. | Alvarez-Moreno, CA. | Le Pape, P. | Parra-Giraldo, CM.

doi: 10.1186/s12866-019-1482-y

P192

J. Antimicrob. Chemother. 2019, 74, 2230-2238.

Precise genome editing using a CRISPR-Cas9 method highlights the role of CoERG11 amino acid substitutions in azole resistance in Candida orthopsilosis.

Morio, F. | Lombardi, L. | Binder, U. | Loge, C. | Robert, E. | Graessle, D. | Bodin, M. | Lass-Flörl, C. | Butler, G. | Le Pape, P.

doi: 10.1093/jac/dkz204

P191

La Lettre de l'Infectiologue • Tome XXXIV - n° 3 - mai-juin 2019.

Brain abscess to Rasamsonia argillacea in a patient with chronic granulomatous disease.

Paret, R. | Le Scornet, T. | Deschanvre, C. | Lecomte, R. | Gaborit, B. | Lavergne, R.-A. | Jeddi, F. | Le Pape, P. | Boutoille, D.

P190

J. Cyst. Fibros. 2019, 18, 212-220.

Prevalence, geographic risk factor, and development of standardized protocol for fungal isolation in cystic fibrosis: results from the international prospective study "MFIP".

Delhaes, L. | Touati, K. | Faure-Cognet, O. | Cornet, M. | Botterel, F. | Dannaoui, E. | Morio, F. | Le Pape, P. | Grenouillet, F. | Favennec, F. | Legal, S. | Nevez, G. | Duhamel. | Borman, A. | Saegeman, V. | Lagrou, K. | Gomez, E. | Carro, ML. | Canton, R. | Campana, S. | Buzina, W. | Chen, S. | Meyer | W. | Roilides, E. | Simitsopoulou, M. | Manso, E. | Cariani, L. | Bifii, A. | Fiscarelli, E. | Ricciotti, G. | Pihet, M. | Bouchara, J.-P.

doi: 10.1016/j.jcf.2018.10.001

P189

J. Antimicrob. Chemother. 2019, 74, 1884-1889.

One-year prospective survey of azole resistance in Aspergillus fumigatus at a French cystic fibrosis reference centre: prevalence and mechanisms of resistance.

Lavergne, R.-A. | Morio, F. | Danner-Boucher, I. | Horeau-Langlard, D. | David, V. | Hagen, F. | Meis, JF. | Le Pape, P.

doi: 10.1093/jac/dkz144

P188

 Int. J. Infect. Dis. 2019, 81, 85-90. 

First case of Aspergillus caelatus airway colonization in a Chronic Obstructive Pulmonary Disease patient.

Le Pape, P. | Ximenes, R. M. | Ariza, B. | Iriarte, J. | Alvarado, J. | Robert, E. | Sierra, C. | Montanez, A., Alvarez-Moreno, C.

doi: 10.1016/j.ijid.2019.01.043

P187

Mycologia 2019, 111, 217-224.

Fungicide-driven alterations in azole-resistant Aspergillus fumigatus are related to vegetable crops in Colombia, South America.

Alvarez-Moreno, C. | Lavergne, R.-A. | Hagen, F. | Morio, F. | Meis, J.F. | Le Pape, P.

doi: 10.1080/00275514.2018.1557796