Defaux, J. | IICIMED

Defaux, J.

Publications

P127

Bioorg. Med. Chem. Lett. 2014, 24, 3748-3752.

Discovery of (7-aryl-1,5-naphthyridin-2-yl)ureas as dual inhibitors of ERK2 and Aurora B kinases with antiproliferative activity against cancer cells.

Defaux, J. | Antoine, M. | Logé, C. | Le Borgne, M. | Schuster, T. | Seipelt, I. | Aicher, B. | Teifel, M. | Günther, E. | Gerlach, M. | Marchand, P.

P124

ChemMedChem 2014, 9, 217-232.

Discovery of 7-Aryl-Substituted (1,5-Naphthyridin-4-yl)ureas as Aurora Kinase Inhibitors. 

Defaux, J. | Antoine, M. | Le Borgne, M. | Schuster, T. | Seipelt, I. | Aicher, B. | Teifel, M. | Günther, E. | Gerlach, M. | Marchand, P.

Autres publications scientifiques

Brevets

B15.

Novel Naphthyridine derivatives and the use thereof as kinase inhibitors.

Gerlach, M. | Schuster, T. | Marchand, P. | Defaux, J. | Seipelt, I. | Polymeropoulos, E. | Müller, G. | Günther, E.

PCT Int. Appl. WO 2011064250, 2011.

Thèse

T24.

Synthèse et évaluation pharmacologique de composés azahétérocycliques à visée antitumorale.

Defaux, J.

Nantes, date de soutenance : 4 décembre 2009.