Cojean, S. | IICIMED

Cojean, S.

Publications

P300

RSC Med. Chem. 2025, 16, 3746–3763. 

 Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2-a]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy

Tisseur, L. | Logé, C. | Cojean, S. | Gassama, K. | Karcher, L. | Pagniez, F. | Cavé, C. | Bernadat, G. | Loiseau, P. M. | Bach, S. | Thiéfaine, J. | Bonnet, J. | Picot, C. | Tomasoni, C. | Leclercq, O. | Baratte, B. | Robert, T. | Le Pape, P. | Rachidi, N. | Bazin, M.-A. | Marchand, P.

https://doi.org/10.1039/D5MD00257E

P290

ChemMedChem. 2025, 20, e202400862.

Investigating the C2 modulation of the imidazo[1,2-a]pyrazine-based hit compound CTN1122: synthesis, in vitro antileishmanial activity, cytotoxicity and casein kinase 1 inhibition.

Tisseur, L. | Cojean, S. | Gassama, K. | Logé, C. | Pagniez, F. | Cavé, C. | Bernadat, G. | Loiseau, P.M. | Bach, S. | Thiéfaine, J. | Picot, C. | Tomasoni, C. | Leclercq, O. | Baratte, B. | Robert, T. | Le Pape, P. | Rachidi, N. | Bazin, M.-A. | Marchand, P.

https://doi.org/10.1002/cmdc.202400862

P287

Eur. J. Med. Chem. Rep. 2024, 12, 100228.

Biological properties and in silico studies of thiazolopyrimidine derivatives active against visceral and cutaneous Leishmania spp. amastigote forms.

Bayaraktar, G. | Marchand, P. | Barbosa, E.G. | da Silva, M.C. | Weber, K.C. | Cojean, S. | Saylam, M. | Istanbullu, H.

https://doi.org/10.1016/j.ejmcr.2024.100228.

P269

Nat. Prod. Res. 2023

Phytochemical, antileishmanial, antifungal and cytotoxic profiles of Thymelaea tartonraira (L.) All. extracts.

Soltani,S | Koubaa, I. | Cojean, S. | Picot, C. | Marchand, P. | Allouche, N.

https://doi.org/10.1080/14786419.2023.2252153

P238

Med. Chem. Lett. 2021, 47,  128196.

Anti-protozoal and anti-fungal evaluation of 3,5-disubstituted 1,2-dioxolanes. Bioorg.

Pinet, A. | Cojean, S. | Nguyen, L. T. | Vásquez-Ocmín, P. | Maciuk, A. | Loiseau, P. M. | Le Pape, P. | Figadère, B. | Ferrié, L.

doi: 10.1016/j.bmcl.2021.128196

P231

Eur. J. Med. Chem. 2021, 210, 112956.

In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition.

Bazin, M.-A. | Cojean, S. | Pagniez, F. | Bernadat, G. | Cavé, C. | Ourliac-Garnier, I. | Nourrisson, M.-R. | Morgado, C. | Picot, C. | Leclercq, O. | Baratte, B. | Robert, T. | Späth, G.F. | Rachidi, N. | Bach, S. | Loiseau, P.M. | Le Pape, P. | Marchand, P.

doi: 10.1016/j.ejmech.2020.112956

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