Le Baut, G. | IICIMED

Le Baut, G.

Publications

P223

Pharmaceuticals. 2020, 13, 186.

Optimization, Antifungal Activity, Selectivity, and CYP51 Binding of New 2-Aryl-3-azolyl-1-indolyl-propan-2-ols.


doi:10.3390/ph13080186

P76

Bioorg. Med. Chem., 2009, 17(18), 6715-6727.

Synthesis and structure-activity relationships of N-aryl(indol-3-yl)glyoxamides as antitumor agents.


P63

 J. Enz. Inh. Med. Chem.2008, 23(5), 686-695.

Side chain modifications of (indol-3-yl)glyoxamides as antitumor agents.


P60

J. Enz. Inh. Med. Chem. 2008, 23(5), 728-738.

N-Pyridinyl(methyl)-indole-1- or 3-propanamides and propenamides acting as topical and systemic anti-inflammatory inhibitors.


P58

J. Enz. Inh. Med. Chem. 2007, 22(5), 667-676.

Synthesis and biological evaluation of 3-(azolylmethyl)-1H-indoles and 3-(alpha-azolylbenzyl)-1H-indoles as selective aromatase inhibitors. 


https://pubmed.ncbi.nlm.nih.gov/18035835/

P57

Bioorg. Med. Chem. Lett. 2007,17(13), 3686-3689.

Synthesis and antifungal activities of new fluconazole analogues with azaheterocycle moiety.


P51

Bioorg. Med. Chem. Lett. 2006, 16, 1134-1137.

Synthesis and biologicol evaluation of 5-[(aryl)(1H-imidazol-1-yl)methyl]-1H-indoles: Potent and selective aromatase inhibitors.


P50

Tetrahedron Lett. 2006, 47, 6479-6483.

Efficient microwave-assisted synthesis of 2-phenyl-1-(1H-indol-1-yl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol derivatives with potential antifungal activity.

 


P45

J. Enz. Inh. Med. Chem. 2005, 20, 581-585.

Three-Dimensional Model of Cytochrome P450 Human Aromatase.


P40

Mycology 2004, 11 (supplement 1), 43.

Antifungal activity of new azolylindole derivatives against Candida and Aspergillus. Proceedings of the 10th Congress of the European Confederation of Medical


P39

J. Enz. Inh. Med. Chem. 2004, 19, 451-457.

Synthesis and antileishmanial activity of 3-imidazolylalkylindoles. Part I.


P37

J. Enz. Inh. Med. Chem. 2004, 19, 549-557.

2- and 3-[(Aryl)(azolyl)methyl]indoles as potential non-steroidal aromatase inhibitors.


P35

Med. Chem. Lett. 2004, 14, 5441-5444.

New N-pyridinyl(methyl)-indolalkanamides acting as topical inflammation inhibitors. Bioorg.


P33

Eur. J. Med. Chem. 2003, 38, 711-718.

Synthesis and antileismanial activity of new imidazolidin-2-one derivatives.


P32

Eur. J. Med. Chem. 2003, 38, 75-87.

Synthesis and antifungal activity of new 1-halogenobenzyl-3-imidazolylmethylindole derivatives.


P30

Bioorg. Med. Chem. Lett. 2003, 13, 1553-1555.

Preparation and Pharmacological Profile of 7-(a-Azolylbenzyl)-1H-Indoles and Indolines as New Aromatase Inhibitors.


P28

J. Enz. Inh. Med. Chem. 2003, 18, 155-158.

Retinoic acid metabolism inhibition by 3-azolylmethyl-1H-indoles and 2,3 or 5-(a-azolylbenzyl)-1H-indoles.


P26

J. Enz. Inh. Med. Chem. 2003, 18, 201-208.

New N-pyridinyl (methyl) N1-substituted-3-indolylpropanamides acting as topical and systemic inflammation inhibitors.


P24

J. Enz. Inh. Med. Chem. 2003, 18, 253-257.

Potential Inhibitors of Angiogenesis. Part II: 3-(Azolylmethylene)-2,3-dihydrobenzo[b]furan-2-ones.


P23

J. Enz. Inh. Med. Chem. 2003, 18, 243-252. 

Potential Inhibitors of Angiogenesis. Part I: 3-(Imidazol-4(5)-yl methylene)indolin-2-ones.


Autres publications scientifiques

Brevets

B9.

Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition.


Brevet US 2004067998 A1 publié le 8 avril 2004.

B8.

Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition.


Brevet CN 1473160A publié le 4 février 2004.

B6.

New azolyl-substituted indole derivatives and analogs, useful as antifungal and antiparasitic drugs effective e.g. against Candida albicans, Aspergillus fumigatus and Leishmania.


Brevet EP 1322638 publié le 2 juillet 2003.

B5.

Indole derivatives and their use as antifungal and/or antiparasitic agents.


Brevet CA 2 423 151 A1 publié le 21 mars 2003.

B4.

Nouveaux dérivés de 3-aryl-2,5-dihydroxy-1,4-benzoquinones, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.


Fr. Pat. n° 02.01409, 06 Feb. 2002.

B2.

Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition.



Brevet PCT WO 02/24685 A1 déposé le 21 septembre 2001, publié le 28 mars 2002.

B1.

Composition pharmaceutique antifongique et/ou antiparasitaire et nouveaux dérivés de l'indole à titre de principes actifs d'une telle composition


Brevet FR 2 814 073 - A1 déposé le 21 septembre 2000, publié le 22 mars 2002.

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