RSC Med. Chem. 2025, 16, 3746–3763. 

 Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2-a]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy

ChemMedChem. 2025, 20, e202400862.

Investigating the C2 modulation of the imidazo[1,2-a]pyrazine-based hit compound CTN1122: synthesis, in vitro antileishmanial activity, cytotoxicity and casein kinase 1 inhibition.

Phytochem. Lett. 2022, 50, 57-60.

Amino ether analogues of 4,4′-dihydroxy-3-methoxy-6,7′-cyclolignan and their activity against drug-resistant bacteria. 

Molecules 2021, 26, 6572.

Dibenzofuran derivatives inspired from cercosporamide as dual inhibitors of Pim and CLK1 kinases.

Med. Chem. Res. 2021, 30, 152-162.

Antimicrobial and anti-leishmanial activities of extracts and some constituents from the leaves of Solanum chrysotrichum Schldl.

Eur. J. Med. Chem. 2021, 210, 112956.

In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition.

Pharmaceuticals 2019, 12, 169.

Biological evaluation of arylsemicarbazone derivatives as potential anticancer agents.

Curr. Top. Med. Chem. 2019, 19, 1075-1091.

5-Nitro-thiophene-thiosemicarbazone derivatives present antitumor activity mediated by apoptosis and DNA intercalation.

Tetrahedron Lett. 2018, 59, 3519-3523.

Novel approach towards 3,7-disubstituted 1,6-naphthyridin-4(1H)-ones exploiting cross-coupling and SNAr reactions of a dihalogenated compound.

J. Heterocycl. Chem. 2018, 55, 1101-1111.

Design and synthesis of imidazo[1,2-a]pyridines with carboxamide group substitution and in silico evaluation of their interaction with a LuxR-type quorum sensing receptor.

Bioorg. Med. Chem. Lett. 2018, 28, 2250-2255.

Benzofuro[3,2-d]pyrimidines inspired from cercosporamide CaPkc1 inhibitor: synthesis and evaluation of fluconazole susceptibility restoration.

X-Ray Struct. Anal. Online 2017, 33, 41-43.

Crystal structure of N-(7-{[2-(dimethylamino)ethyl]amino}-1-methyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-3,4,5-trimethoxybenzamide.

Eur. J. Med. Chem. 2016, 119, 17-33.

Novel 1,6-naphthyridin-2(1H)-ones as potential anticancer agents targeting Hsp90.

Anticancer Res. 2016, 36, 1621-1630.

Discovery of (imidazo[1,2-a]pyrazin-6-yl)ureas as antiproliferative agents targeting P53 in non-small cell lung cancer cell lines.

Tetrahedron 2015, 71, 3303-3313.

Efficient one-pot synthesis of 3,7-disubstituted 1,6-naphthyridin-2(1H)-ones through regioselective palladium-catalyzed cross-coupling and SNAr reactions.

Eur. J. Med. Chem. 2015, 103, 381-395.

Synthesis, antileishmanial activity and cytotoxicity of 2,3-diaryl- and 2,3,8-trisubstituted imidazo[1,2-a]pyrazines.

Eur. J. Org. Chem. 2014, 7, 1487-1495.

Differential functionalization of 1,6-naphthyridin-2(1H)-ones through sequential one-pot Suzuki-Miyaura cross-couplings.

Eur. J. Med. Chem., 2013, 69, 823-832.

Synthesis and antiproliferative activity of benzofuran-based analogs of cercosporamide against non-small cell lung cancer cell lines.

Tetrahedron Lett., 2013, 54, 5378-5382. 

Exploration of versatile reactions on 2-chloro-3-nitroimidazo[1,2-a]pyridine: expanding structural diversity of C2- and C3-functionalized imidazo[1,2-a]pyridines.

 Eur. J. Med. Chem., 2012, 58, 543-556. 

Synthesis and biological evaluation of 2,3-diarylimidazo[1,2-a]pyridines as antileishmanial agents.