Thiéfaine, J.

Technician

Publications

P309

Bioorg. Med. Chem. 2026, 139, 118678.

5,6,7,8-Tetrahydroimidazo[1,2-a]pyrazine-based thiosemicarbazones as anti-Trypanosoma cruzi agents.

Saraiva de Araujo Neta, M. Coelho, M-C. Coutinho, F. N. Alves Pereira, V. R. Hernandes, M. Z. Ferreira, R. S. Sales Junior, P. A. Murta, S. M. F. Ourliac-Garnier, I. Bazin, M.-A. Courtioux, B. Boudot, C. Santos, A. C. da S. Gomes Rebello Ferreira, L. F. Martins, L. C. Thiéfaine, J. Brenot, E. Mendonça Junior, F. J. B. da Silva, T. G. de Faria, A. R. Marchand, P.

https://doi.org/10.1016/j.bmc.2026.118678

P300

RSC Med. Chem. 2025, 16, 3746–3763. 

 Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2-a]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy

Tisseur, L. Logé, C. Cojean, S. Gassama, K. Karcher, L. Pagniez, F. Cavé, C. Bernadat, G. Loiseau, P. M. Bach, S. Thiéfaine, J. Bonnet, J. Picot, C. Tomasoni, C. Leclercq, O. Baratte, B. Robert, T. Le Pape, P. Rachidi, N. Bazin, M.-A. Marchand, P.

https://doi.org/10.1039/D5MD00257E

P290

ChemMedChem. 2025, 20, e202400862.

Investigating the C2 modulation of the imidazo[1,2-a]pyrazine-based hit compound CTN1122: synthesis, in vitro antileishmanial activity, cytotoxicity and casein kinase 1 inhibition.

Tisseur, L. Cojean, S. Gassama, K. Logé, C. Pagniez, F. Cavé, C. Bernadat, G. Loiseau, P.M. Bach, S. Thiéfaine, J. Picot, C. Tomasoni, C. Leclercq, O. Baratte, B. Robert, T. Le Pape, P. Rachidi, N. Bazin, M.-A. Marchand, P.

https://doi.org/10.1002/cmdc.202400862

P240

Molecules 2021, 26, 6572.

Dibenzofuran derivatives inspired from cercosporamide as dual inhibitors of Pim and CLK1 kinases.

Dao, V. H. Ourliac-Garnier, I. Logé, C. McCarthy, F. O. Bach, S. da Silva, T. G. Denevault-Sabourin, C. Thiéfaine, J. Baratte, B. Robert, T. Gouilleux, F. Brachet-Botineau, M. Bazin, M.-A. Marchand, P.

doi: 10.3390/molecules26216572