Le Borgne, M. | IICIMED

Le Borgne, M.

Publications

P208

J. Enzym. Inhib. Med. Chem. 2020, 35, 398-403.

Biological exploration of a novel 1,2,4-triazole-indole hybrid molecule as antifungal agent.


doi: 10.1080/14756366.2019.1705292

P127

Bioorg. Med. Chem. Lett. 2014, 24, 3748-3752.

Discovery of (7-aryl-1,5-naphthyridin-2-yl)ureas as dual inhibitors of ERK2 and Aurora B kinases with antiproliferative activity against cancer cells.


P124

ChemMedChem 2014, 9, 217-232.

Discovery of 7-Aryl-Substituted (1,5-Naphthyridin-4-yl)ureas as Aurora Kinase Inhibitors. 


P91

ChemMedChem, 2011, 6, 816-825.

Design, synthesis and in vitro antifungal activity of 1-[(4-substituted benzyl)methylamino]-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ols.


P79

Bioorg. Med. Chem. Lett., 2009, 19(20), 5833-5836.

Design of new antifungal agents: synthesis and evaluation of 1-[(1H-indol-5-ylmethyl)amino]-2-phenyl-3-(1H-1,2,4-triazol-1-yl)propan-2-ols.


P77

J. Enz. Inh. Med. Chem., 2009, 24(5), 1067-1075.

Design, synthesis and evaluation of 3-(imidazol-1-ylmethyl)indoles as antileishmanial agents. Part II.


P74

Bioorg. Med. Chem. Lett., 2009, 19(2), 301-304

Synthesis and structure-activity relationships of 2-phenyl-1-[(pyridinyl- and piperidinylmethyl)amino]-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as antifungal agents.


P70

Bioorg. Med. Chem. Lett. 2008, 18(6), 1820-1824.

Design, synthesis, and evaluation of 1-(N-benzylamino)-2-phenyl-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as antifungal agents.


P69

Bioorg. Med. Chem. Lett. 2008, 18(16), 4713-4715.

Synthesis of 6- or 4-functionalized indoles via a reductive cyclization approach and evaluation as aromatase inhibitors.


P58

J. Enz. Inh. Med. Chem. 2007, 22(5), 667-676.

Synthesis and biological evaluation of 3-(azolylmethyl)-1H-indoles and 3-(alpha-azolylbenzyl)-1H-indoles as selective aromatase inhibitors. 


https://pubmed.ncbi.nlm.nih.gov/18035835/

P57

Bioorg. Med. Chem. Lett. 2007,17(13), 3686-3689.

Synthesis and antifungal activities of new fluconazole analogues with azaheterocycle moiety.


P52

J. Enz. Inh. Med. Chem. 2006, 21, 277-283.

3-(a-Azolylbenzyl)indoles: in vitro and in vivo anti-Leishmania activity and mechanism of action.


P51

Bioorg. Med. Chem. Lett. 2006, 16, 1134-1137.

Synthesis and biologicol evaluation of 5-[(aryl)(1H-imidazol-1-yl)methyl]-1H-indoles: Potent and selective aromatase inhibitors.


P50

Tetrahedron Lett. 2006, 47, 6479-6483.

Efficient microwave-assisted synthesis of 2-phenyl-1-(1H-indol-1-yl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol derivatives with potential antifungal activity.

 


P48

SAR and QSAR in Environ. Res. 2006, 17, 299-309.

3D-QSAR COMSIA study on 3-azolylmethylindoles as anti-leishmanial agents.


P45

J. Enz. Inh. Med. Chem. 2005, 20, 581-585.

Three-Dimensional Model of Cytochrome P450 Human Aromatase.


P40

Mycology 2004, 11 (supplement 1), 43.

Antifungal activity of new azolylindole derivatives against Candida and Aspergillus. Proceedings of the 10th Congress of the European Confederation of Medical


P39

J. Enz. Inh. Med. Chem. 2004, 19, 451-457.

Synthesis and antileishmanial activity of 3-imidazolylalkylindoles. Part I.


P37

J. Enz. Inh. Med. Chem. 2004, 19, 549-557.

2- and 3-[(Aryl)(azolyl)methyl]indoles as potential non-steroidal aromatase inhibitors.


P32

Eur. J. Med. Chem. 2003, 38, 75-87.

Synthesis and antifungal activity of new 1-halogenobenzyl-3-imidazolylmethylindole derivatives.


Autres publications scientifiques

Brevets

B9.

Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition.


Brevet US 2004067998 A1 publié le 8 avril 2004.

B8.

Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition.


Brevet CN 1473160A publié le 4 février 2004.

B6.

New azolyl-substituted indole derivatives and analogs, useful as antifungal and antiparasitic drugs effective e.g. against Candida albicans, Aspergillus fumigatus and Leishmania.


Brevet EP 1322638 publié le 2 juillet 2003.

B5.

Indole derivatives and their use as antifungal and/or antiparasitic agents.


Brevet CA 2 423 151 A1 publié le 21 mars 2003.

B2.

Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition.



Brevet PCT WO 02/24685 A1 déposé le 21 septembre 2001, publié le 28 mars 2002.

B1.

Composition pharmaceutique antifongique et/ou antiparasitaire et nouveaux dérivés de l'indole à titre de principes actifs d'une telle composition


Brevet FR 2 814 073 - A1 déposé le 21 septembre 2000, publié le 22 mars 2002.

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